Here are a list of the best glyphs to use on your Discipline Priest in Cataclysm patch 4.1. If you don’t already have a talent build be sure to check out this Discipline Priest Talent Build for use with the glyphs in this guide.
For your Prime Glyphs you’ll pretty much want to have the following glyphs, there isn’t too much room to mess around with different ones.
Glyph of Penance – Reduces the cooldown of Penance by 2 sec.
Glyph of Power Word: Barrier – Increases the healing received while under the Barrier by 10%.
Glyph of Prayer of Healing – Your Prayer of Healing spell also heals an additional 20% of its initial heal over 6 sec.
You’ll have two main glyphs for this section that you pretty much want to have and the other one is your choice.
Glyph of Divine Accuracy – Increases your chance to hit with your Smite and Holy Fire spells by 18%.
Glyph of Prayer of Mending – The first charge of your Prayer of Mending heals for an additional 60%.
Some other choices you might want to consider are:
Glyph of Dispel Magic – Your Dispel Magic spell also heals your target for 3% of maximum health when you successfully dispel a magical effect.
Glyph of Mass Dispel – Reduces the cast time of Mass Dispel by 1 sec.
Glyph of Fade – Reduces the cooldown of your Fade spell by 9 sec.
Glyph of Holy Nova – Reduces the global cooldown of your Holy Nova by .5 sec.
What you choose to use for your Minor Glyphs is totally up to you. Here are the ones that I would suggest using.
Glyph of Fortitude – Reduces the mana cost of your Power Word: Fortitude spell by 50%.
Glyph of Levitate – Your Levitate spell no longer requires a reagent.
Glyph of Shadowfiend - Receive 5% of your maximum mana if your Shadowfiend dies from damage.
Glyph of Fading – Reduces the mana cost of your Fade spell by 30%.